5 Rare Old Medicines That Had Horrific Side Effects

Medicine has come a long way from the “good old days” of garlic-filled masks and astringent herbal teas. Even in relatively recent times, drugs have been used which have horrific effects on the human body. But—and this is a big but—they can and often do work. At the time, they were the best we had, despite the bizarre ways that they could kill you.

1. Metrazol.

In 1926, F. Hildebrandt tested a new drug on animals and found two primary clinically significant effects. In high doses, it caused epileptic-like convulsions. In more reasonable doses, it merely stimulated the heart and increased respiration in cases of depressant poisoning.